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miscarriage

Miscarriage

Having a miscarriage can be a very traumatic experience. It is distressing and bereavement, even when it occurs in the early stages of pregnancy. However, it may be of some comfort to know that miscarriage, particularly in the early months is very common.
The vast majority of women go on to have successful pregnancies after experiencing a miscarriage. For this reason, having one or two early miscarriages is not usually seen as a reason for medical investigation.

Causes of miscarriage

  • The vast majority of miscarriages are due to one-off genetic disorder of the egg or sperm which makes the continued development of the fertilized egg impossible.
    The egg or sperm may lack some vital genetic information, or more commonly, an extra chromosomes is present.
    Research has shown that chromosomal abnormalities are detected in up to 60% of recognised miscarriages.
  • The failure of the fertilized egg to implant successfully in the lining of the uterus.
  • The mother having a low level of progestrone, which is needed to sustain the pregnancy.
Later miscarraige( after 14 weeks) can be the result of:
  • An abnormality in the uterus such as large fibroid.
  • A weak (incompetent) cervix. This is a condition in which the cervix dilates instead of remaining tightly closed during pregnancy.

 

Miscarrage investigation

Miscarraige Investigation is the testing phase of the program, conducted between pregnancies. Both partners participate in a series of tests with the hope of determining a cause.

Few of the recommended tests are discussed below:

Genetic Testing

Genetic abnormalities are one of the more common causes for miscarriage. The expression "It's nature's way..." is often accurate; the body has rejected the fetus because it was not quite right.
The test known as a karyotype involves analysing your and your partner's chromosomes for abnormalities.

Anatomical tests

An ultrasound is performed to investigate the uterus, tubes and ovaries looking for structural abnormalities.

Haemotological tests

The white blood cells in our blood can be divided into many different subsets, each with a specific role. Testing of these different subsets before and during pregnancy can help us identify women at high risk of miscarriage and who need special support in the next pregnancy.

Biochemical tests

Some disorders to do with copper metabolism and selenium intake can contribute to miscarriage and are easily screened for with a simple blood test.

Histological tests

For a successful and ongoing implantation of the embryo to occur, the uterus lining (or endometrium) must develop in time to accept the new embryo. The time that follows ovulation is known as the luteal phase of the menstrual cycle. A biopsy of the endometrium during the late luteal phase tells us about the adequacy of ovulation and the adequacy of the response in the uterus. A defect of the luteal phase may contribute to miscarriage.

NOTE: All this information is taken from the Sydney IVF miscarraige Investigation Program. To have more information on this You can go directly from here to their website www.miscarriage.com.au

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